Pediatric asthma and autism—genomic perspectives

Pediatric asthma and autism—genomic perspectives

High-throughput technologies, ranging from microarrays to NexGen sequencing of RNA and genomic DNA, have opened new avenues for exploration of the pathobiology of human disease. Comparisons of the architecture of the genome, identification of mutated or modified sequences, and pre-and post- transcriptional regulation of gene expression as disease specific biomarkers are revolutionizing our unde...

asthma control challenges: global and national perspectives

Comorbidities of pediatric asthma: A narrative review

Background: Asthma is one of the most common persistent inflammatory respiratory disorders. Comorbidities are relatively common in asthma. The aim of this review study was to find comorbid disorders in children with asthma. Methods: For the purpose of this review, we searched databases including Scopus, Google scholar, PubMed, SID, Irandoc and up-to-date. Key words for the search included chil...

Asthma diagnosis and treatment Perspectives in asthma

Although allergen exposure can clearly aggravate the condition of sensitized patients with asthma, there is uncertainty and controversy about exactly which allergen avoidance interventions should be recommended to patients with asthma. Interventions that appear logical may fail to be clinically efficacious for several reasons. Although narrow interventions, such as allergen-impermeable mattress...

Pediatric Asthma

Asthma is a chronic inflammatory disease of the airways that is characterized by reversible airway obstruction, airway hyperresponsiveness to stimuli, variable airway resistance and flow rates, and transient increases in lung volume. Classic symptoms include cough, wheezing, dyspnea, and chest tightness [1]. Worldwide, asthma prevalence is increasing, with generally higher prevalence rates in w...